diff --git a/src/Parsers/ASTWithAlias.cpp b/src/Parsers/ASTWithAlias.cpp
index 20f647fb575..88f6568a719 100644
--- a/src/Parsers/ASTWithAlias.cpp
+++ b/src/Parsers/ASTWithAlias.cpp
@@ -48,4 +48,9 @@ void ASTWithAlias::appendColumnName(WriteBuffer & ostr) const
         appendColumnNameImpl(ostr);
 }
 
+void ASTWithAlias::appendColumnNameWithoutAlias(WriteBuffer & ostr) const
+{
+    appendColumnNameImpl(ostr);
+}
+
 }
diff --git a/src/Parsers/ASTWithAlias.h b/src/Parsers/ASTWithAlias.h
index 7a272a157e2..ea4419402b0 100644
--- a/src/Parsers/ASTWithAlias.h
+++ b/src/Parsers/ASTWithAlias.h
@@ -21,6 +21,7 @@ public:
     using IAST::IAST;
 
     void appendColumnName(WriteBuffer & ostr) const final;
+    void appendColumnNameWithoutAlias(WriteBuffer & ostr) const final;
     String getAliasOrColumnName() const override { return alias.empty() ? getColumnName() : alias; }
     String tryGetAlias() const override { return alias; }
     void setAlias(const String & to) override { alias = to; }
diff --git a/src/Parsers/IAST.cpp b/src/Parsers/IAST.cpp
index e223235b8e4..6451a9d0c0d 100644
--- a/src/Parsers/IAST.cpp
+++ b/src/Parsers/IAST.cpp
@@ -109,6 +109,14 @@ String IAST::getColumnName() const
 }
 
 
+String IAST::getColumnNameWithoutAlias() const
+{
+    WriteBufferFromOwnString write_buffer;
+    appendColumnNameWithoutAlias(write_buffer);
+    return write_buffer.str();
+}
+
+
 void IAST::FormatSettings::writeIdentifier(const String & name) const
 {
     switch (identifier_quoting_style)
diff --git a/src/Parsers/IAST.h b/src/Parsers/IAST.h
index bed6c5bcdf9..54e08b2700e 100644
--- a/src/Parsers/IAST.h
+++ b/src/Parsers/IAST.h
@@ -41,11 +41,18 @@ public:
 
     /** Get the canonical name of the column if the element is a column */
     String getColumnName() const;
+    /** Same as the above but ensure no alias names are used. This is for index analysis */
+    String getColumnNameWithoutAlias() const;
     virtual void appendColumnName(WriteBuffer &) const
     {
         throw Exception("Trying to get name of not a column: " + getID(), ErrorCodes::LOGICAL_ERROR);
     }
 
+    virtual void appendColumnNameWithoutAlias(WriteBuffer &) const
+    {
+        throw Exception("Trying to get name of not a column: " + getID(), ErrorCodes::LOGICAL_ERROR);
+    }
+
     /** Get the alias, if any, or the canonical name of the column, if it is not. */
     virtual String getAliasOrColumnName() const { return getColumnName(); }
 
diff --git a/src/Storages/MergeTree/KeyCondition.cpp b/src/Storages/MergeTree/KeyCondition.cpp
index ead93a6e1d9..eb58b2911c9 100644
--- a/src/Storages/MergeTree/KeyCondition.cpp
+++ b/src/Storages/MergeTree/KeyCondition.cpp
@@ -444,7 +444,7 @@ bool KeyCondition::addCondition(const String & column, const Range & range)
   */
 bool KeyCondition::getConstant(const ASTPtr & expr, Block & block_with_constants, Field & out_value, DataTypePtr & out_type)
 {
-    String column_name = expr->getColumnName();
+    String column_name = expr->getColumnNameWithoutAlias();
 
     if (const auto * lit = expr->as<ASTLiteral>())
     {
@@ -607,7 +607,7 @@ bool KeyCondition::canConstantBeWrappedByMonotonicFunctions(
     if (strict)
         return false;
 
-    String expr_name = node->getColumnName();
+    String expr_name = node->getColumnNameWithoutAlias();
     const auto & sample_block = key_expr->getSampleBlock();
     if (!sample_block.has(expr_name))
         return false;
@@ -675,7 +675,7 @@ bool KeyCondition::canConstantBeWrappedByFunctions(
     if (strict)
         return false;
 
-    String expr_name = ast->getColumnName();
+    String expr_name = ast->getColumnNameWithoutAlias();
     const auto & sample_block = key_expr->getSampleBlock();
     if (!sample_block.has(expr_name))
         return false;
@@ -934,7 +934,7 @@ bool KeyCondition::isKeyPossiblyWrappedByMonotonicFunctionsImpl(
       * Therefore, use the full name of the expression for search.
       */
     const auto & sample_block = key_expr->getSampleBlock();
-    String name = node->getColumnName();
+    String name = node->getColumnNameWithoutAlias();
 
     auto it = key_columns.find(name);
     if (key_columns.end() != it)
diff --git a/tests/queries/0_stateless/01649_with_alias_key_condition.reference b/tests/queries/0_stateless/01649_with_alias_key_condition.reference
new file mode 100644
index 00000000000..5816b4eb49b
--- /dev/null
+++ b/tests/queries/0_stateless/01649_with_alias_key_condition.reference
@@ -0,0 +1 @@
+3	4
diff --git a/tests/queries/0_stateless/01649_with_alias_key_condition.sql b/tests/queries/0_stateless/01649_with_alias_key_condition.sql
new file mode 100644
index 00000000000..b813e6ee84f
--- /dev/null
+++ b/tests/queries/0_stateless/01649_with_alias_key_condition.sql
@@ -0,0 +1,11 @@
+drop table if exists alias_key_condition;
+
+create table alias_key_condition ( i int, j int ) engine MergeTree order by i;
+
+insert into alias_key_condition values (1, 2), (3, 4);
+
+set force_primary_key = 1;
+
+with i as k select * from alias_key_condition where k = 3;
+
+drop table if exists alias_key_condition;