diff --git a/src/Access/SettingsConstraints.cpp b/src/Access/SettingsConstraints.cpp
index c9a6b6f6b7a..7dce4d96b33 100644
--- a/src/Access/SettingsConstraints.cpp
+++ b/src/Access/SettingsConstraints.cpp
@@ -156,6 +156,25 @@ bool SettingsConstraints::checkImpl(const Settings & current_settings, SettingCh
 {
     const String & setting_name = change.name;
 
+    if (setting_name == "profile")
+    {
+        /// TODO Check profile settings in Context::setProfile(...), not here. It will be backward incompatible.
+        const String & profile_name = change.value.safeGet<String>();
+        const auto & profile_settings_changes = manager->getProfileSettings(profile_name);
+        try
+        {
+            /// NOTE We cannot use CLAMP_ON_VIOLATION here, because we cannot modify elements of profile_settings_changes
+            for (auto change_copy : *profile_settings_changes)
+                checkImpl(current_settings, change_copy, THROW_ON_VIOLATION);
+        }
+        catch (Exception & e)
+        {
+            e.addMessage(", while trying to set settings profile {}", profile_name);
+            throw;
+        }
+        return true;
+    }
+
     bool cannot_cast;
     auto cast_value = [&](const Field & x) -> Field
     {
diff --git a/tests/queries/0_stateless/01187_set_profile_as_setting.reference b/tests/queries/0_stateless/01187_set_profile_as_setting.reference
new file mode 100644
index 00000000000..ae1cc97819b
--- /dev/null
+++ b/tests/queries/0_stateless/01187_set_profile_as_setting.reference
@@ -0,0 +1,8 @@
+0	0
+0	0
+OK
+1	1
+2	1
+2	1
+OK
+1	1
diff --git a/tests/queries/0_stateless/01187_set_profile_as_setting.sh b/tests/queries/0_stateless/01187_set_profile_as_setting.sh
new file mode 100755
index 00000000000..8247ab8870a
--- /dev/null
+++ b/tests/queries/0_stateless/01187_set_profile_as_setting.sh
@@ -0,0 +1,15 @@
+#!/usr/bin/env bash
+
+CURDIR=$(cd "$(dirname "${BASH_SOURCE[0]}")" && pwd)
+. "$CURDIR"/../shell_config.sh
+
+$CLICKHOUSE_CLIENT -n -m -q "select value, changed from system.settings where name='readonly';"
+$CLICKHOUSE_CLIENT -n -m -q "set profile='default'; select value, changed from system.settings where name='readonly';"
+$CLICKHOUSE_CLIENT -n -m -q "set profile='readonly'; select value, changed from system.settings where name='readonly';" 2>&1| grep -Fa "Cannot modify 'send_logs_level' setting in readonly mode" > /dev/null && echo "OK"
+CLICKHOUSE_CLIENT=$(echo ${CLICKHOUSE_CLIENT} | sed 's/'"--send_logs_level=${CLICKHOUSE_CLIENT_SERVER_LOGS_LEVEL}"'/--send_logs_level=fatal/g')
+$CLICKHOUSE_CLIENT -n -m -q "set profile='readonly'; select value, changed from system.settings where name='readonly';"
+
+${CLICKHOUSE_CURL} -sS "${CLICKHOUSE_URL}&query=select+value,changed+from+system.settings+where+name='readonly'"
+${CLICKHOUSE_CURL} -sS "${CLICKHOUSE_URL}&profile=default&query=select+value,changed+from+system.settings+where+name='readonly'"
+${CLICKHOUSE_CURL} -sS "${CLICKHOUSE_URL}&profile=readonly&query=select+value,changed+from+system.settings+where+name='readonly'" 2>&1| grep -Fa "Cannot modify 'readonly' setting in readonly mode" > /dev/null && echo "OK"
+echo "select value, changed from system.settings where name='readonly';" | ${CLICKHOUSE_CURL} -sSg "${CLICKHOUSE_URL}&profile=readonly" -d @-