diff --git a/src/Interpreters/LogicalExpressionsOptimizer.cpp b/src/Interpreters/LogicalExpressionsOptimizer.cpp
index 9e30cac2e19..bd24e13b129 100644
--- a/src/Interpreters/LogicalExpressionsOptimizer.cpp
+++ b/src/Interpreters/LogicalExpressionsOptimizer.cpp
@@ -1,13 +1,17 @@
 #include <Interpreters/LogicalExpressionsOptimizer.h>
+#include <Interpreters/IdentifierSemantic.h>
+#include <DataTypes/DataTypeLowCardinality.h>
 #include <Core/Settings.h>
 
 #include <Parsers/ASTFunction.h>
 #include <Parsers/ASTSelectQuery.h>
 #include <Parsers/ASTLiteral.h>
+#include <Parsers/ASTIdentifier.h>
 
 #include <Common/typeid_cast.h>
 
 #include <deque>
+#include <vector>
 
 #include <base/sort.h>
 
@@ -32,8 +36,9 @@ bool LogicalExpressionsOptimizer::OrWithExpression::operator<(const OrWithExpres
     return std::tie(this->or_function, this->expression) < std::tie(rhs.or_function, rhs.expression);
 }
 
-LogicalExpressionsOptimizer::LogicalExpressionsOptimizer(ASTSelectQuery * select_query_, UInt64 optimize_min_equality_disjunction_chain_length)
-    : select_query(select_query_), settings(optimize_min_equality_disjunction_chain_length)
+LogicalExpressionsOptimizer::LogicalExpressionsOptimizer(ASTSelectQuery * select_query_,
+    const TablesWithColumns & tables_with_columns_, UInt64 optimize_min_equality_disjunction_chain_length)
+    : select_query(select_query_), tables_with_columns(tables_with_columns_), settings(optimize_min_equality_disjunction_chain_length)
 {
 }
 
@@ -196,13 +201,39 @@ inline ASTs & getFunctionOperands(const ASTFunction * or_function)
 
 }
 
+bool LogicalExpressionsOptimizer::isLowCardinalityEqualityChain(const std::vector<ASTFunction *> & functions) const
+{
+    if (functions.size() > 1)
+    {
+        /// Check if identifier is LowCardinality type
+        auto & first_operands = getFunctionOperands(functions[0]);
+        const auto * identifier = first_operands[0]->as<ASTIdentifier>();
+        if (identifier)
+        {
+            auto pos = IdentifierSemantic::getMembership(*identifier);
+            if (!pos)
+                pos = IdentifierSemantic::chooseTableColumnMatch(*identifier, tables_with_columns, true);
+            if (pos)
+            {
+                if (auto data_type_and_name = tables_with_columns[*pos].columns.tryGetByName(identifier->shortName()))
+                {
+                    if (typeid_cast<const DataTypeLowCardinality *>(data_type_and_name->type.get()))
+                        return true;
+                }
+            }
+        }
+    }
+    return false;
+}
+
 bool LogicalExpressionsOptimizer::mayOptimizeDisjunctiveEqualityChain(const DisjunctiveEqualityChain & chain) const
 {
     const auto & equalities = chain.second;
     const auto & equality_functions = equalities.functions;
 
     /// We eliminate too short chains.
-    if (equality_functions.size() < settings.optimize_min_equality_disjunction_chain_length)
+    if (equality_functions.size() < settings.optimize_min_equality_disjunction_chain_length &&
+            !isLowCardinalityEqualityChain(equality_functions))
         return false;
 
     /// We check that the right-hand sides of all equalities have the same type.
diff --git a/src/Interpreters/LogicalExpressionsOptimizer.h b/src/Interpreters/LogicalExpressionsOptimizer.h
index 4991d31f8b1..a8a0d186394 100644
--- a/src/Interpreters/LogicalExpressionsOptimizer.h
+++ b/src/Interpreters/LogicalExpressionsOptimizer.h
@@ -1,6 +1,7 @@
 #pragma once
 
 #include <Parsers/IAST.h>
+#include <Interpreters/DatabaseAndTableWithAlias.h>
 
 #include <string>
 #include <vector>
@@ -36,7 +37,7 @@ class LogicalExpressionsOptimizer final
 
 public:
     /// Constructor. Accepts the root of the query DAG.
-    LogicalExpressionsOptimizer(ASTSelectQuery * select_query_, UInt64 optimize_min_equality_disjunction_chain_length);
+    LogicalExpressionsOptimizer(ASTSelectQuery * select_query_, const TablesWithColumns & tables_with_columns_, UInt64 optimize_min_equality_disjunction_chain_length);
 
     /** Replace all rather long homogeneous OR-chains expr = x1 OR ... OR expr = xN
       * on the expressions `expr` IN (x1, ..., xN).
@@ -79,6 +80,9 @@ private:
       */
     bool mayOptimizeDisjunctiveEqualityChain(const DisjunctiveEqualityChain & chain) const;
 
+    /// Check if is LowCardinality OR chain
+    bool isLowCardinalityEqualityChain(const std::vector<ASTFunction *> & functions) const;
+
     /// Insert the IN expression into the OR chain.
     static void addInExpression(const DisjunctiveEqualityChain & chain);
 
@@ -96,6 +100,7 @@ private:
     using ColumnToPosition = std::unordered_map<const IAST *, size_t>;
 
     ASTSelectQuery * select_query;
+    const TablesWithColumns & tables_with_columns;
     const ExtractedSettings settings;
     /// Information about the OR-chains inside the query.
     DisjunctiveEqualityChainsMap disjunctive_equality_chains_map;
diff --git a/src/Interpreters/TreeRewriter.cpp b/src/Interpreters/TreeRewriter.cpp
index eb713019306..c61ba9c3286 100644
--- a/src/Interpreters/TreeRewriter.cpp
+++ b/src/Interpreters/TreeRewriter.cpp
@@ -1246,7 +1246,7 @@ TreeRewriterResultPtr TreeRewriter::analyzeSelect(
     translateQualifiedNames(query, *select_query, source_columns_set, tables_with_columns);
 
     /// Optimizes logical expressions.
-    LogicalExpressionsOptimizer(select_query, settings.optimize_min_equality_disjunction_chain_length.value).perform();
+    LogicalExpressionsOptimizer(select_query, tables_with_columns, settings.optimize_min_equality_disjunction_chain_length.value).perform();
 
     NameSet all_source_columns_set = source_columns_set;
     if (table_join)