diff --git a/programs/CMakeLists.txt b/programs/CMakeLists.txt
index 152da46ebf2..31943ef7dae 100644
--- a/programs/CMakeLists.txt
+++ b/programs/CMakeLists.txt
@@ -322,6 +322,12 @@ endif()
 
 clickhouse_add_executable (clickhouse main.cpp)
 
+if (NOT USE_STATIC_LIBRARIES AND SPLIT_SHARED_LIBRARIES)
+    # Shared split (dev) build: In CI, the server is run with custom LD_LIBRARY_PATH. This makes the harmful env check re-execute the
+    # process in a clean environment but as in CI the containing directory is not included in DT_RUNPATH/DT_RPATH, the server won't come up.
+    target_compile_definitions(clickhouse PRIVATE DISABLE_HARMFUL_ENV_VAR_CHECK)
+endif ()
+
 # A library that prevent usage of several functions from libc.
 if (ARCH_AMD64 AND OS_LINUX AND NOT OS_ANDROID)
     set (HARMFUL_LIB harmful)
diff --git a/programs/main.cpp b/programs/main.cpp
index 175504a85fa..27e17cfd2e0 100644
--- a/programs/main.cpp
+++ b/programs/main.cpp
@@ -345,6 +345,7 @@ struct Checker
 ;
 
 
+#ifndef DISABLE_HARMFUL_ENV_VAR_CHECK
 /// NOTE: We will migrate to full static linking or our own dynamic loader to make this code obsolete.
 void checkHarmfulEnvironmentVariables(char ** argv)
 {
@@ -396,6 +397,7 @@ void checkHarmfulEnvironmentVariables(char ** argv)
         _exit(error);
     }
 }
+#endif
 
 }
 
@@ -422,7 +424,9 @@ int main(int argc_, char ** argv_)
     ///  will work only after additional call of this function.
     updatePHDRCache();
 
+#ifndef DISABLE_HARMFUL_ENV_VAR_CHECK
     checkHarmfulEnvironmentVariables(argv_);
+#endif
 
     /// Reset new handler to default (that throws std::bad_alloc)
     /// It is needed because LLVM library clobbers it.